A prion is a misfolded protein that has the ability to transmit its misfolded shape onto normal variants of the same protein, causing progressive neurodegenerative diseases such as Creutzfeldt-Jakob disease.
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Additional Source Prion (Wikipedia)History section (edge: proposed-by, Prusiner)
Sources
1. Prion (Wikipedia)
WikipediaLead section (entity-description)
A prion is a misfolded protein that can induce abnormal folding of specific normal cellular proteins, causing disease.
Lead section (proposed-year)
The term prion was coined in 1982 by Stanley B. Prusiner, who proposed the protein-only hypothesis of infectious disease.
Lead section (proposed-by)
The term prion was coined in 1982 by Stanley B. Prusiner, who proposed the protein-only hypothesis of infectious disease.
Proposed By: Stanley B. Prusiner, History section (edge: proposed-by, Prusiner)
In 1982, Stanley B. Prusiner of the University of California, San Francisco, announced that his team had purified the hypothetical infectious protein, which did not appear to be present in healthy hosts.
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