A prion is a misfolded protein that has the ability to transmit its misfolded shape onto normal variants of the same protein, causing progressive neurodegenerative diseases such as Creutzfeldt-Jakob disease.
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Source Prion (Wikipedia)
Source Prion (Wikipedia)
Long-Form Articles
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Additional Source Prion (Wikipedia)History section (edge: proposed-by, Prusiner)
Sources
1. Prion (Wikipedia)
WikipediaLead section (entity-description)
A prion is a misfolded protein that can induce abnormal folding of specific normal cellular proteins, causing disease.
Lead section (proposed-year)
The term prion was coined in 1982 by Stanley B. Prusiner, who proposed the protein-only hypothesis of infectious disease.
Lead section (proposed-by)
The term prion was coined in 1982 by Stanley B. Prusiner, who proposed the protein-only hypothesis of infectious disease.
Proposed By: Stanley B. Prusiner, History section (edge: proposed-by, Prusiner)
In 1982, Stanley B. Prusiner of the University of California, San Francisco, announced that his team had purified the hypothetical infectious protein, which did not appear to be present in healthy hosts.
Belongs To: Biology, Lead, sentence 1
A prion ( ) is a misfolded protein that induces folding problems in normal variants of the same protein, leading to cellular death.
Belongs To: Medicine, Lead, sentence 2
Prions are responsible for prion diseases, which are fatal and transmissible neurodegenerative diseases affecting animals, including humans.
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