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The Disulphide Bonds of Insulin

Biochemical Journal

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The 1955 paper completing Frederick Sanger's determination of the complete amino acid sequence of bovine insulin, identifying the three disulfide bonds linking the hormone's two chains, published in the Biochemical Journal, volume 60, issue 4, pages 541 to 556.

Facts
Author
A. P. Ryle, Frederick Sanger, L. F. Smith and Ruth Kitai
Publisher
Biochemical Journal
Publication Year
1955
Source Type
Journal article
Reliability Tier
1
The primary published paper completing the first full sequencing of a protein, the achievement's own foundational source.
Sources
The Disulphide Bonds of Insulin
A. P. Ryle, Frederick Sanger, L. F. Smith and Ruth Kitai, Biochemical Journal, 1955
Claims Backed By This Source (13 claims)

This source backs 13 claims across the atlas. As facts: 9 well-attested. As cited relationships: 1 holds, 1 connected. Plus 2 entities citing it as a general reference with no single fact or relationship attached.

Disposition By Topic

  • Sources, 6 claims: 6 well-attested.
  • Theories, 5 claims: 3 well-attested, 1 connected, 1 general references.
  • Scientists, 2 claims: 1 holds, 1 general references.

Holds

1

Connected

1

General References

2
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